Megakayocyte Mature
The megakaryocyte begins its development from a megakaryoblast which closely resembles all other “blast” cells. Early in development it undergoes mitotic divisions to increase its numbers but finally it undergoes only endomitotic divisions. This results in no additional cells but the cell increases dramatically in size and nuclear complexity. The cytoplasm is abundant and finley granular; the nucleus remains single but it is highly lobulated.