Biophysical Chemistry

Temple University Department of Chemistry

DNA photolyase binds its substrate by baseflipping. We explore this process using fluorescent base analogs like 2-aminopurine. 1789-1793 (2004)

 

The Stanley Laboratory

· Light-driven DNA repair by DNA photolyase

· Mechanistic Studies (ultrafast laser spectroscopy)

· Electronic structure by Stark spectroscopy and TD-DFT calculations

· Site-directed Mutagenesis

· Role of FAD in catalysis

· Substrate dynamics

 

· Electronic properties of flavins and flavoproteins

· Measurement of charge transfer properties

· Stark spectroscopy and TD-DFT calculations

· Photophysical properties of fluorescent nucleic base analogs

· Two photon properties

· Electronic structure by Stark spectroscopy and TD-DFT calculations

· Single molecule studies of monomers and oligomers

Robert J Stanley, Ph.D.

250B Beury Hall

Department of Chemistry

1901 N. 13th St.

Philadelphia PA 19122

To contact us:

Phone: 215-204-2027

Fax: 215-204-1532

E-mail: rstanley@temple.edu

Mees et al, Science v. 306, pp 1789-1793 (2004)