BIOLOGY 3096 (W204) -
Instructor: Dr. Sheffield: Office, Bio-Life 311, Phone: 204 8839, e-mail jbs@temple.edu
Laboratory Coordinator::Jennifer Emtage: Office, Bio-Life 248a, Phone 204 8870, e-mail jemtage@temple.edu
Texts:
(1) Karp, G. Cell and Molecular Biology, 6th edition. J. Wiley & Sons, publisher. This is a new edition, but it is not that different from the 5th edition. I believe that either one will be fine for this course. The book will be available in the Temple Bookstore, of course, but you can also get it online. However, you should be aware that I have worked out a couple of interesting options with the publisher, and I don't know if they will be available in other venues. I haven't seen the bookstore prices yet, so you might want to check.
B. The Loose-Leaf. This includes the full text, but unbound, and punched for a 3-hole loose-leaf binder (not provided). I have been told that this version should result in a roughly $50 saving over option A. It would include Take Note.
C. Online: “Course Smart” allows you to “subscribe” –that is, you have access to the text, fully searchable, for 180 days. They also have a download option, in which you can put the book on your own hard drive. Somehow, there is a timer in this version as well, so it becomes inaccessible after the time is up.
D. You can also use the used book market, or the international version (if you can get it). Prices and amount of yellow highlighter will vary.
Here is an attempt at a summary:
|
Karp, Cell and
Molecular Biology, 6th edition |
|||
|
Bound version with Wiley Plus |
Bookstore or phone order |
ISBN 9780470483374 |
Price 164.95 list |
|
Loose-leaf version |
Bookstore or phone order |
978-0-470-89465-1 |
114.95 list |
|
Course Smart , http://www.coursesmart.com/9780470042175 5th edition (either online or download) |
Web Site |
9780470042175 |
80.50 |
|
http://www.coursesmart.com/9780470483374 (online only) 6th edition |
Web Site |
9780470564851 |
85.50 |
|
Desktop Downloadable version Store.vitalsource.com |
Web Site |
9780470563892 |
102.50 |
|
Jones/Bartlet lab notebook. |
Bookstore |
|
14.00 |
|
Lab Manual |
Conwell/Ritter copy center |
|
About 16.00 |
Students in a hurry can buy directly from Wiley, by calling Customer service 800 225-5945, and purchase with a credit card. They just need to be sure to give them the correct ISBN to get the version they want with the proper components, hard copy text, loose-leaf version of just WileyPlus access card version. If you buy directly from Wiley the price would be similar to what the bookstore charges. You can not do this through the Wiley web site. You must use the old fashioned technology of the telephone.
(2) You will also be expected to
purchase a lab manual packet from the
(3) you will need the laboratory
safety manual, if you don't already have it,.
(4) A Lab notebook with carbons and removable
pages.
Course Information:
This is a basic introductory course in modern cellular biology. You should
have taken Biology 1111 and 2112, and Inorganic and Organic Chemistry. and should have had or be taking Physics. If you do
not meet these prerequisites, you should withdraw from the course
My goals in this course are to present the evidence for our
present understanding of Cell Structure, and to discuss the nature of research
as well as the results. For this reason, I devote a substantial portion of the
course to analysis of techniques of Cell Biology and to the history of
discovery. Naturally, this can't be done for every subject, but I try to
establish an environment in which it is expected that any student might
interrupt and ask me to justify any statement by citing an experiment.
Similarly, this is one of the approaches that I will use in exams.
I treat the text as a resource. I expect you to be able to use it to fill in
areas I might have glossed over, and to provide an explanation that might be
complementary to any that I provide. There are no formal reading
assignments. I have listed readings
as a guide to the material. You may
find additional information elsewhere in the text.
Grading will be based primarily on a class curve. About 10% of the class will
receive A, 20% B, 50% C, and the rest something else. There will be two exams
during the semester, each worth 20% of the final grade. The final exam will be
informally divided into two parts; the first will cover the last third of the
semester, and the second will be a cumulative review. The final is worth 40% of
the grade. The laboratory is a required part of the course,
you will receive a number grade which will count for 20% of the course grade.
Thus, the maximum number of points you can accumulate will be 500. In previous interations of the course, students who have received a
total of about 450 points have received A's, 400 points have received B's, and
300 points have received C's. More details of the grading procedure will be
discussed in class. There will be no makeup
exams. If you are forced to miss one of the mid semester exams, your grade
will be based on the others, as long as I receive appropriate explanations
(Doctor's note, etc.). In the absence of an excuse, the exam will count as a
zero. If you miss both of the mid semester exams, you should drop the course.
Because of the number of students, exams will be multiple choice.
After each exam the correct answers will be posted outside the lab. For the
mid-semester exams, students who feel that their answer to a particular
question is correct even though it is not the same as the posted answer may
write up a detailed justification for their answer and give it to me. Students
will have two class days after the exam is returned to hand in written
justification for changes in the grading. Because of time constraints, I will
not be able to review final exams in this way.
Since we all hate multiple choice exams, I have come up with a way to try to beat the system. Here’s the deal. Each week, you may send me a single multiple choice question based on that week’s material.
Provide:
1.. the question,
2. five possible answers, and
3. your choice for the correct answer
4. the rationale for your answer. (you will not receive credit if this is omitted)
You will then receive 1 point towards your total grade for each question. You can submit only one question per week, and it must be based on that week’s material. You may not accumulate questions and then submit them all at once. Questions should be addressed to a special e-mail address, jbs.questions@gmail.com, and must have “Multiple Choice” in the subject line. Since I will be collecting these automatically into a folder, they must have those words in the subject line. I will ignore any others. My purpose is severalfold. First, this is a subterfuge to force you to think about the material as it goes along. Secondly, it gives me some idea of how well you are following the course. Thirdly, it gives you the experience of designing a multiple choice question (It’s not that easy!). Fourthly, it saves me a little work in making up questions, since I will use some of the questions in my exams (generally with some editing). Fifthly, if your question appears on the exam, you will already know the answer! The maximum number you can receive is 10 points.
Office Hours: I will have office hours from 10-11:30 on Mondays, and
We will be using Blackboard for posting notes, lab information and general
class communication via e-mail. I hope that this will be an opportunity for you
to share questions and answers with me and the laboratory staff. There will be
more on this as the course progresses. I have posted a copy of this syllabus on
the Blackboard site and on the following website: http://astro.temple.edu/~jbs/courses/204intro.html
. Within the syllabus are links to the lecture notes and to some supplementary
material. The lecture notes are essentially copies of the images that I present
during lecture. It will be up to you to fill in with the text and jokes. As an
experiment, I am leaving up the notes from the 2008 version of the course so
that you can look ahead if you want. I will update these as the course
progresses. Be aware that I have rearranged the course material a bit this year,
so you may have to hunt for the appropriate lecture notes.
Any student who has a need for accommodation
based on disability should contact me privately as soon as possible. Also
contact the office of Disability Resources at 204-1280.
Biology 3096 - Cell Structure - Syllabus, Approximate.
A few definitions of symbols in the reading lists:
-> from this page until the next one on the list
ff "and pages following"
|
Date |
Topic |
Karp, 6th edition |
|
August 29 |
1-30 |
|
|
31 |
728-> |
|
|
September 2 |
-> |
|
|
7 |
743 |
|
|
9 |
Principles of Molecular Organization: Bonds, Carbohydrates, Lipids, Nucleic Acids |
31-49 |
|
12 |
||
|
14 |
76 |
|
|
16 |
77-82 |
|
|
19 |
Separations :Electrophoresis, |
Lab Manual, 749-751 |
|
21 |
744-> |
|
|
23 |
Chromatography, Immunological Techniques, Affinity , Enzyme Characteristics I |
749, 94-> |
|
25 |
-> |
|
|
28 |
->107 |
|
|
30 |
|
|
|
October 3 |
EXAM I |
|
|
5 |
125-> |
|
|
7 |
146 |
|
|
10 |
239-258 |
|
|
12 |
147-> Web Site for Ion Channel |
|
|
14 |
164 |
|
|
17 |
260-268, 311-325 |
|
|
19 |
486-494, 274-277 |
|
|
21 |
281-> |
|
|
24 |
|
|
|
26 |
|
|
|
28 |
|
|
|
31 |
More
on the Lysosome, protein turnover |
|
|
November 2 |
->366 |
|
|
4 |
368-> |
|
|
7 |
EXAM II |
|
|
9 |
384 |
|
|
11 |
107-117 |
|
|
14 |
183-> |
|
|
16 |
208 |
|
|
18 |
214-236 |
|
|
21 |
Cell to Cell Signals Ligand-Cell Surface Interactions I, Steroid Receptors |
Figure 12.44, p525, 616-> |
|
23 |
657 |
|
|
28 |
307, |
|
|
30 |
571-> |
|
|
December 2 |
579, 653-657 |
|
|
5 |
662->687 |
|
|
7 (last day of classes) |
Cancer II |
|
The
Final Examination will be December 14 (Wednesday) at 10:30 a.m.
|
Week of: |
Subject |
|
September 5 |
Introduction, Microscopes I - Bright Field |
|
September 12 |
Microscopes II - Phase and Darkfield |
|
September 19 |
Protein Purification - Column |
|
September 26 |
Electrophoresis - |
|
October 3 |
Protein Purification Simulation |
|
October 10 |
Cell Culture |
|
October 17 |
Microscopes |
|
October 26 |
Properties of Muscle Cells |
|
October 31 |
Cell Fractionation I |
|
November 7 |
Cell Fractionation II |
|
November 14 |
Image Processing |