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Sol Sherry Thrombosis Research Center

Temple University School of Medicine


Venue: Kresge Building, Classroom C

Tuesday Noon Seminar

List of Speakers   

2005-2006

2006-2007

2007-2008



Speakers    2005-2006

Sep. 27, 2005              The 24th Annual Jeanette Piperno Memorial Lecture
                                    David Ginsburg, MD. Professor, University of Michigan, MI
                                    Title: Disorders of hemostasis due to genes outside of the coagulation system.

Oct. 11, 2005              Kusumam Joseph, Ph.D. Assistant Professor, Medical University of South Carolina
                                    Title: Pathways of bradykinin formation in plasma.

Oct. 18, 2005              Khalil Bdeir, Ph.D. Assistant Professor, University of Pennsylvania
                                    Title:
The Patho-biology of Neutrophil Defensins.

Oct. 25, 2005              Morris J. Birnbaum, MD, Ph.D. Professor, University of Pennsylvania
                                    Title: Regulation of Growth and Metabolism by Akt/PKB

Nov. 1, 2005               Sriram Krishnaswamy, Ph.D. Professor, University of Pennsylvania
                                    Title: Coagulation Protease Specificity and Function.

Nov. 8, 2005               Scott L. Diamond, Ph.D. Professor, University of Pennsylvania
                                   
Title: Blood coagulation microarrays and high throughput phenotyping.

Nov. 15, 2005             J. Evan Sadler, MD, Ph.D. Professor, Washington University, St. Louis, MO
                                    Title: von Willebrand factor and ADAMTS13.

Nov. 22, 2005            Tracee Panetti, Ph.D. Assistant Professor, Temple University
                                   Title: Regulators of Endothelial Cell Migration.                       

Nov. 29, 2005             David Pritchard, Ph.D. Axis Shield Diagnostics, UK
                                    Title: Measurement of activated Factor XII in Humans. How XIIa exists in vivo!

Dec. 6, 2005               Mark Kahn, MD. Assistant Professor, University of Pennsylvania
                                    Title: Hematopoietic contribution to vascular development.
        
Dec. 13, 2005             ASH 2005, Atlanta, GA

Dec. 16, 2005             George Tuszynski, Ph.D. Professor, Temple University
Friday                         Title:
Interaction of angiocidin with the extracellular matrix and its role in angiogenesis.

Jan. 31, 2006              Fredda London, Ph.D. Associate Professor, Temple University
                                   Title: Platelet subpopulations: Are all platelets created equal?

Feb. 14, 2006             Steven McKenzie, MD, Ph.D. Professor, Thomas Jefferson University
                                   Title: Heparin-Induced Thrombocytopenia and Thrombosis.

Feb. 21, 2006             Rodney M. Camire, Ph.D. Assistant Professor, University of Pennsylvania
                                   Title: Mechanism Regulating the Factor V Procofactor to Cofactor Transition.

Feb. 28, 2006             Andrew Chow, Ph.D. Application Scientist, Biacore Inc., NJ
                                   Title: To Affinity and Beyond.

Mar. 7, 2006              Heinrich Roder, Ph.D. Chair, Biomolecular Structure and Function Program, Fox Chase Cancer Center
                                   Title: Structural and biophysical studies indicate that activation of factor XI
                                   involves a major conformational change.

Mar. 14, 2006            Bruce Sachais, MD, Ph.D. Assistant Professor,  University of Pennsylvania
                                   Title: Platelet Factor 4 (PF4) in the Pathogenesis of Atherosclerosis and HIT: Size and Proportion may Matter.

Mar. 21, 2006             Stewart-Niewiarowski Award and Lecture
                                   Maureane Hoffman, MD, Ph.D. Professor, Duke University, Durham, NC
                                   Title: Rethinking The Coagulation Cascade.

Mar. 29, 2006            Victor Marder, MD. Professor, University of California LA, CA
Wednesday 3 pm        Title: Plasmin: Pre-Clinical Studies.

Apr. 11, 2006             David W. Speicher, Ph.D. Professor, The Wistar Institute
                                   Title: Investigating human diseases using novel proteomics approaches.

Apr. 25, 2006            David Ho, Ph.D. Director of Hematology, Cellphire, Inc. MD
                                  Title: Thrombosomes(TM): a novel platelet derived hemostatic agent.

May 2, 2006              Joel S. Bennett, MD. Professor, University of Pennsylvania
                                  Title: Modulating Platelet Integrin Function Using Exogenous Transmembrane Domain-Related Peptides.

May 9, 2006              John W. Weisel, Ph.D. Professor, University of Pennsylvania
Kresge B                    Title: Fundamental aspects of controlled and specific intermolecular interactions revealed from single molecule studies.

May 23, 2006            Hong Wang, MD, Ph.D. Associate Professor, Temple University
                                  Title: Homocysteine and Endothelial Injury.

May 30, 2006            Michael Bromberg, MD, Ph.D. Associate Professor, Temple University
                                  Title: Tissue factor-mediated signaling in malignancy and beyond.

June 6, 2006              Barrie Ashby, Ph.D. Professor, Temple University
Kresge D                   Title: The prostaglandin EP3 receptor and platelets.

June 13, 2006            Salim Merali, Ph.D.  Associate Professor, Temple University
                                  Title: Application of Differential Proteomics to Study Drug Mechanisms and Biomarker Discovery.

June 20, 2006            Eleanor S. Pollak, MD.   Associate Professor, University of Pennsylvania
                                  Title: Functional Polymorphisms in Human Procoagulant Factor VII.

June 27, 2006            Vinod Vijayan, K., Ph.D. Assistant Professor, Baylor College of Medicine, TX
                                  Title: 
Serine/Threonine phosphatases: Are they important for platelet functions?


Interested in talking to seminar speakers while they visit the Center?

Contact : Duraiswamy Navaneetham (dnavanee@temple.edu) at 215-707-4155


Sol Sherry Thrombosis Research Center
3400 North Broad Street, 3rd Floor OMS
Philadelphia, PA 19140

Speakers    2006-2007


Sep.  26, 2006:   
The 25th Annual Jeanette Piperno Memorial Lecture.
Dr. Garret A. FitzGerald, M.D. Professor of Medicine, Elmer Bobst Professor of Pharmacology. University of Pennsylvania School of Medicine                     Philadelphia, PA
Title: Cardiovascular consequences of prostaglandin inhibition.

Oct.  3, 2006   
Dr. Donna Wolfe, Ph. D, Assistant Professor of Medicine, Thomas Jefferson University, Philadelphia, PA.
Title: Akt-dependent pathways in platelet function.

Oct. 10, 2006      
Dr. Fayez F. Safadi, Ph. D. Associate Professor
Department of Anatomy, Temple University School of Medicine, Philadelphia, PA.     
 Title: "Matrix and Transmembrane Proteins-Integrin Interaction in Osteoblasts"

Oct. 17, 2006   
Dr. Bradford Jameson, Ph.D. Professor of Biochemistry,  MCP Hahnemann University, Philadelphia, PA.
Title: Serotonin mediates the immune response.

Oct. 24, 2006   
Dr. Masumi Eto, Ph. D. Associate Professor of  Medicine, Thomas Jefferson University, Philadelphia, PA.
Title: Mechanisms for Ca2+ sensitizing force of vascular smooth muscle.

Oct. 31, 2006   
Dr. Robert W. Colman, MD. Sol Sherry Professor of Medicine, Temple University School of Medicine, Philadelphia, PA.   
Title: New insights from the structure function analysis of the catalytic region of human platelet PDE3A.

Nov. 7, 2006   
Dr. Alan D. Michelson, M.B., B.S. Director, Center for Platelet Function Studies, Professor of Pediatrics, Medicine, and Pathology, Vice Chair                           for Academic Affairs, Department of Pediatrics, University of Massachusetts Medical School, MA.
Title: Measurement of Platelet function in patients with coronary artery disease: How and Why?

November 14, 2006   
Dr. Yale Nemerson, MD. Philip J. and Harriet L. Goodhart Professor of Medicine and Biochemistry, Mount Sinai School of Medicine,  NY.
Title: "Tissue Factor and Lipids: A Coordinated View."

November  28, 2006   
Dr. Marilyn Woolkalis, Ph. D. Associate Professor, Department of Physiology, Thomas Jefferson University, Philadelphia, PA.
Title: Regulating prothrombotic signaling in human endothelial cells

December 5, 2006   
Dr. Barbara Schick, Ph. D. Professor of Medicine, Thomas Jefferson University, Philadelphia, PA.
Title: Role of secratory granule proteoglycan in platelet  function.

December 19, 2006   
Dr. Zissimos Mourelatos, M.D., Assistant Professor, Department of Pathology and Laboratory Medicine, University of Pennsylvania, PA.
Title: It is a small RNA world, after all

January 23, 2007   
Dr. Doina Ganea, Ph. D., Professor, Department of Physiology, Temple University School of Medicine, Philadelphia, PA.   
Title: Neuropeptides and Autoimmune Diseases

January 30, 2007   
Dr. Fabio M. Pulcinelli PhD, MD, Department of Experimental Medicine, University "La Sapienza" Viale Regina Elena, Roma, Italy
Title: "Impaired platelet COX-1/aspirin interaction in patients under chronic treatment"

February 6, 2007       
Dr. Evgeny Krynetskiy, Ph.D. Associate Professor Temple University School of PharmacyPhiladelphia, PA
Title: "Pharmacogenomics: search for individualized therapy".

February 13, 2007   
Dr. Lin Wu, MD, PhD, Research Associate, Albany Medical College, Cardiovascular Department, Albany, NY
Title: CHARACTERIZATION OF TRANSGENIC MICE WITHA HYPOMORPHIC NADPH-CYTOCHROME P-450REDUCTASE ALLELE FUNCTIONAL STUDY OF P37 PROTEIN DURING THE TUMOR METASTASIS    

February 20, 2007       
Dr. Raul A. DeLa Cadena, M.D. Associate Professor of Physiology, and Thrombosis Research, Temple University School of Medicine
Title: “Thrombospondin-1/Neutrophil Interaction: A Pro-Inflammatory Pathway in Rheumatoid Arthritis”

February 27, 2007   
Dr. Michael Autieri, Ph.D. Assistant Professor of Physiology, Temple University School of Medicine, Philadelphia, PA.   
Title: "the role of inflammatory proteins in vascular proliferative diseases"

March 6, 2007   
Dr. Victor Rizzo, Ph.D., Associate Professor, Anatomy and Cell Biology, Temple University School of Medicine, Philadelphia, PA.   
Title: "Participation of endothelial cell membrane rafts and caveolae in β1 integrin-mediated mechanotransduction".

March 13, 2007   
Dr. Louis M Weiner, M.D. Professor and Vice President, Translational research and Chairman, Department of Medical Oncology, Temple University School of Medicine, Philadelphia, PA.   
Title: "Unconjugated Antibodies for Cancer Therapy".

March 20, 2007   
Dr. Satoru Eguchi, M.D., Ph.D, Associate Professor of Physiology, Cardiovascular Research Center, Temple University School of Medicine, Philadelphia, PA.   
Title: Novel signal transduction mechanism of GPCR-induced vascular and endothelial dysfunction.

April 3, 2007       
Dr. Zia Shariat-Madar, Ph.D The University of Mississippi, Department of Pharmacology School of Pharmacy
Title: Increased prolylcarboxypeptidase activation is an independent risk factor for the development of inflammation

April 10, 2007   
Dr. Douglas Cines, M.D., Professor, Department of Pathology, Hospital of University of Pennsylvania, PA.
Title:    Heparin-Induced Thrombocytopenia.

April 17, 2007   
Dr. Leon Salganecoff, Ph.D. Professor Emeritus, Department of Pharmacology, Temple University School of Medicine, Philadelphia, PA.   
Title: “Dynamics of the adhesion between platelets during deconsolidation induced by PGE1

April 24, 2007   
Dr. Paul Bray, MD., Professor of Medicine, Chief of Hematology and  Director of Cardeza Foundation for Hematologic Research, Thomas Jefferson University, Philadelphia, PA.
Title: Measuring Extremes of Platelet Reactivity

May 22, 2007
Dr. Alexandra Monroy PhD., Assistant Professor, Deaprtment of Anatomy and Cell Biology, Temple University School of Medicine, Philadelphia, PA.
Title: Chromatin remodeling factor SRCAP


2006-7 Seminar coordinator

Dr. Mohammad M. H. Khan MD., Ph.D. 

Sol Sherry Thrombosis Research Center, 3400 North Broad Street,
Philadelphia, PA 19140



Speakers    2007-2008

September 20, 2007 – Weidong Xiao, Ph.D.
“AAV Vector: From Basic Science to Gene Therapy”
Children’s Hospital of Philadelphia, Philadelphia

September 28, 2007 – Lawrence Goldfinger
“Developing a new language for cell signaling: Proteomic mapping of Ras signaling networks in vascular function”
Divisions of Rheumatology and Hematology-Oncology
Department of Medicine, University of California, San Diego

October 2, 2007 - X. Long Zheng, M.D, Ph.D.
“Cross Talk Between Procoagulant and Von Willebrand Factor”.
Medical Director, Coagulation Laboratory
The Children's Hospital of Philadelphia
Assistant Professor, Department of Pathology and Laboratory Medicine
The University of Pennsylvania Medical Center, Philadelphia

October 9, 2007 - Wadie F. Bahou, M.D., Professor of Medicine
“Classification of Platelet Disorders using Gene Profiling”
Hematology and Vice Dean, SUNY/Stony Brook, New York

October 23, 2007 – Duraiswamy Navaneetham Ph.D.
"Inhibition of Factor XIa and Trypsin by Kunitz Inhibitors, PN2KPI and BPTI: Role of the P1 Site Residue"
Assistant Professor, Sol Sherry Thrombosis Research Center
Temple University, Philadelphia

October 30, 2007 –  Mohammad M. H. Khan, M.D., Ph.D.
"Role of Bacterial Protease in Septic Shock"   
Assistant Professor, Sol Sherry Thrombosis Research Center
Temple University, Philadelphia

November 6, 2007 - Wolfgang Bergmeier, Ph.D.
“Mice lacking the signaling molecule CalDAG-GEFI represent a novel mouse model for leukocyte adhesion deficiency (LAD)-III”.
Thomas Jefferson University, Dept. of Medicine and Cardeza Foundation, Philadelphia

November 13, 2007 – David Walter Essex, M.D.
"The Role of Reactions Involving Thiols and Disulfides in Platelet Function"
Associate Professor, University of Texas, Department of Medicine/Hematology, San Antonio, TX 

November 16, 2007 - Silvia Muro, Ph.D.
Vesicular trafficking mediated by ICAM-1: A gate for endothelial transport of drugs, leukocytes and fibrin".
Research Assistant Professor of Pharmacology
Institute for Translational Medicine and Therapeutics
Institute for Environmental Medicine, University of Pennsylvania Medical School, Philadelphia, PA

November 20, 2007 – Dr. Satya Kunapuli, Ph.D.
Protein Kinase C deta: At the crossroads of platelet signaling
Professor, Physiology, Professor, Pharmacology
Co-Director, Sol Sherry Thrombosis Research Center
Temple University, Philadelphia
 
December 4, 2007 – Dr. Sriram Krishnaswamy, Ph.D.
“Regulation of the Initiation of Coagulation”
Professor, Howard Hughes Medical Institute, Children's Hospital of Philadelphia, Philadelphia

December 18, 2007 – Dr. Triantafyllos Chavakis
"JAM-C in vascular inflammation"
National Institutes of Health, Bethesda, MD  20892

January 8, 2008 – James Daniels, Ph.D.
“The Role of Cbl Family Members in Platelet Activation”
Professor, Pharmacology
Associate Professor, Sol Sherry Thrombosis Research Center, Philadelphia

January 15, 2008 – A. Koneti Rao, M.D.
“Signaling Defects in Human Platelets: Phospholipase C-ß2 Expression and NFκB”
Director, Sol Sherry Thrombosis Research Center
Section Chief, Hematology, Professor, Medicine
Professor, Sol Sherry Thrombosis Research Center
Professor, Pathology and Laboratory Medicine, Professor, Pharmacology
  Temple University, Philadelphia

January 22, 2008 - – Dr. Charles S. Abrams, Ph.D.
 “How membrane phospholipids affect the platelet cytoskeleton"
Associate Professor of Medicine
University of Pennsylvania, Philadelphia

January 29, 2008 - Linda Knight, Ph.D.
"Radiolabeled Bitistatin: From viper venom to clinical trials as a
diagnostic agent for imaging thrombi in vivo"
Professor of Diagnostic Imaging   
Temple University, Philadelphia

February 5, 2008 – Donald L. Gill, Ph.D
“Novel Transduction Mechanisms Controlling Calcium Signals”
Professor and Chair, Department of Biochemistry,
Temple University School of Medicine, Philadelphia

February 12, 2008 - Dr. Donna Woulfe, Ph.D,
"Akt signaling in platelets:  upstream, downstream and inside-out"
Assistant Professor
Center for Translational Medicine
Jefferson Medical College
Thomas Jefferson University, Philadelphia
         
February 19, 2008 – Syed Ahmad, M.D., Ph.D.
“The Assembly of Coagulation Proteins on the Activated Human Platelet Membranes”
Professor, Sol Sherry Thrombosis Research Center
Professor, Biochemistry
Temple University, Philadelphia

February 26, 2008 - Robert W. Colman, M.D.
“Plasma Kininogen:  A Target for Therapy of Inflammatory and Neoplastic Disorders”
Professor of Medicine, Professor, Physiology
Professor, Microbiology and Immunology
Professor, Fels Institute for Cancer Research and Molecular Biology
Temple University, Philadelphia

March 4, 2008 - Yi Wu, M.D., Ph.D.
“Kininogen Targets Endothelial Progenitor Cells in Angiogenesis: New Life to an Old Story”
Assistant Professor, Sol Sherry Thrombosis Research Center
Temple University, Philadelphia

March 11, 2008 - Mohammad F. Kiani, Ph.D.
“The Inflammatory Response in Normal and Irradiated Tissue”
Professor and Chair, Department of Mechanical Engineering
Temple University, Philadelphia,

March 25, 2008 – M. Anna Kowalska, Ph.D.
“Chemokiens and Thrombogenecity”
Department of Hematology
The Children’s Hospital of Philadelphia, Philadelphia

April 1, 2008 - Michael Bromberg, M.D., Ph.D.
“Role of Tissue Factor-Mediated Signaling in Breast Cancer”
Associate Professor, Medicine
Associate Professor, Sol Sherry Thrombosis Research Center
Temple University, Philadelphia

April 15, 2008 – Rodney M. Camire, Ph.D.
“Targeting the common pathway for improving hemostasis in hemophilia”
Assistant Professor of Pediatrics
Department of Pediatrics
The Children’s Hospital of Philadelphia, Philadelphia

April 22, 2008 – Andrei Thomas-Tikhonenko, Ph.D
“MYC v. Thrombospondin & Co: The miRanda ruling upheld”
Associate Professor of Pathology
Department of Pathobiology
University of Pennsylvania, Philadelphia

April 29, 2008 – Michael P. Reilly, Ph.D.
“Preclinical Mouse Model of Heparin-Induced Thrombocytopenia and Thrombosis”
Associate Professor of Medicine
Cardeza Foundation for Hematologic Research
Jefferson Medical College
Philadelphia

May 6, 2008 – Mauricio J. Reginato, Ph.D.
“Breast Cancer in 3D: Mechanisms of Her2/ErbB2-Mediated Oncogenesis”
Assistant Professor
Department of Biochemistry and Molecular Biology
Drexel University College of Medicine
Philadelphia

May 13, 2008 – Kathy High, M.D.
“Stewart-Niewiarowski Memorial Lecture Award Recipient”
“Gene therapy for genetic disease: the long and winding road”
Professor of Pediatrics
Children’s Hospital of Philadelphia, Philadelphia

May 20, 2008 - Dr. Xiaoping Du, M.D., Ph.D.
“Signaling pathways of platelet adhesion receptors GPIb-IX and integrin alpha IIb/beta 3.”
Professor
Department of Pharmacology
University of Illinois at Chicago, Chicago

May 27, 2008 – Dipali Sinha, Ph.D.
"A tale of one substrate and two enzymes"
Associate Professor, Sol Sherry Thrombosis Research Center
Temple University, Philadelphia

2007-8 Seminar coordinator

Dr. Gauthami Jalagadugula Ph.D. 

Sol Sherry Thrombosis Research Center, 3400 North Broad Street,
Philadelphia, PA 19140



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