
Sol
Sherry Thrombosis Research Center
Temple
University School of Medicine
Venue:
Kresge Building, Classroom C
Tuesday
Noon Seminar
List
of Speakers
Speakers
2005-2006
Sep. 27,
2005 The
24th Annual Jeanette Piperno Memorial Lecture
David
Ginsburg, MD. Professor,
University of Michigan, MI
Title: Disorders of hemostasis due to genes outside of the coagulation
system.
Oct. 11, 2005
Kusumam
Joseph, Ph.D. Assistant Professor, Medical University of South
Carolina
Title:
Pathways of bradykinin formation in plasma.
Oct. 18, 2005
Khalil Bdeir, Ph.D.
Assistant Professor, University of Pennsylvania
Title: The
Patho-biology of Neutrophil Defensins.
Oct. 25, 2005
Morris J. Birnbaum, MD,
Ph.D.
Professor, University of Pennsylvania
Title: Regulation
of
Growth and Metabolism by Akt/PKB.
Nov. 1, 2005 Sriram Krishnaswamy, Ph.D. Professor,
University of Pennsylvania
Title:
Coagulation Protease Specificity and Function.
Nov. 8, 2005
Scott L. Diamond, Ph.D. Professor,
University of
Pennsylvania
Title: Blood
coagulation microarrays and high throughput phenotyping.
Nov. 15, 2005
J. Evan Sadler, MD, Ph.D.
Professor, Washington University, St. Louis, MO
Title: von Willebrand factor and ADAMTS13.
Nov.
22, 2005
Tracee Panetti, Ph.D.
Assistant Professor, Temple University
Title: Regulators of Endothelial Cell
Migration.
Nov. 29, 2005
David Pritchard, Ph.D. Axis
Shield Diagnostics, UK
Dec. 6,
2005
Mark Kahn, MD. Assistant Professor, University of Pennsylvania
Title: Hematopoietic contribution to vascular
development.
Dec. 13, 2005
ASH 2005, Atlanta, GA
Dec. 16, 2005
George Tuszynski, Ph.D.
Professor, Temple University
Friday
Title: Interaction of angiocidin with the extracellular matrix and its
role in angiogenesis.
Jan. 31,
2006
Fredda London, Ph.D.
Associate Professor, Temple University
Title: Platelet subpopulations: Are all
platelets created equal?
Feb. 14,
2006
Steven McKenzie, MD,
Ph.D. Professor, Thomas Jefferson University
Title: Heparin-Induced Thrombocytopenia and
Thrombosis.
Feb. 21,
2006
Rodney M. Camire, Ph.D.
Assistant Professor, University
of Pennsylvania
Title: Mechanism Regulating the Factor V
Procofactor to Cofactor Transition.
Feb. 28,
2006
Andrew Chow,
Ph.D. Application Scientist, Biacore Inc., NJ
Title: To Affinity
and Beyond.
Mar. 7,
2006
Heinrich Roder,
Ph.D. Chair, Biomolecular Structure and Function Program, Fox
Chase Cancer Center
Title: Structural and biophysical studies
indicate that activation of factor XI
involves
a major conformational change.
Mar. 14,
2006 Bruce Sachais, MD, Ph.D.
Assistant Professor, University
of Pennsylvania
Title: Platelet Factor 4 (PF4) in the
Pathogenesis of Atherosclerosis and HIT: Size and Proportion may Matter.
Mar. 21,
2006
Stewart-Niewiarowski
Award and Lecture
Maureane
Hoffman, MD, Ph.D. Professor, Duke University, Durham, NC
Title: Rethinking The Coagulation Cascade.
Mar. 29, 2006
Victor Marder, MD. Professor,
University of California LA, CA
Wednesday 3 pm
Title:
Plasmin: Pre-Clinical Studies.
Apr. 11,
2006 David W. Speicher, Ph.D. Professor,
The Wistar Institute
Title: Investigating human diseases using novel
proteomics approaches.
Apr. 25,
2006
David Ho, Ph.D. Director of Hematology,
Cellphire, Inc. MD
Title:
Thrombosomes(TM): a novel platelet derived hemostatic agent.
May 2,
2006
Joel S. Bennett,
MD. Professor,
University
of Pennsylvania
Title: Modulating Platelet Integrin Function Using
Exogenous Transmembrane Domain-Related Peptides.
May 9,
2006
John W.
Weisel, Ph.D. Professor, University
of Pennsylvania
Kresge B
Title:
Fundamental aspects of controlled and specific intermolecular
interactions revealed from single molecule studies.
May 23,
2006 Hong Wang, MD, Ph.D. Associate
Professor, Temple University
Title: Homocysteine and
Endothelial Injury.
May 30,
2006 Michael Bromberg, MD, Ph.D.
Associate Professor, Temple University
Title: Tissue factor-mediated signaling in malignancy and
beyond.
June 6,
2006
Barrie Ashby, Ph.D.
Professor, Temple University
Kresge D
Title:
The prostaglandin EP3 receptor and platelets.
June 13,
2006 Salim Merali, Ph.D. Associate
Professor, Temple University
Title: Application of Differential Proteomics to Study
Drug Mechanisms and Biomarker Discovery.
June 20,
2006 Eleanor S. Pollak, MD.
Associate
Professor, University
of Pennsylvania
Title: Functional Polymorphisms in Human Procoagulant
Factor VII.
June
27, 2006 Vinod Vijayan, K., Ph.D. Assistant
Professor, Baylor College of Medicine, TX
Title: Serine/Threonine
phosphatases: Are they important for platelet functions?
Interested in
talking to seminar speakers while they visit the Center?
Contact
: Duraiswamy Navaneetham (dnavanee@temple.edu)
at 215-707-4155
Sol
Sherry Thrombosis Research Center
3400 North Broad Street, 3rd Floor OMS
Philadelphia, PA 19140
Speakers
2006-2007
Sep. 26, 2006:
The 25th Annual Jeanette Piperno
Memorial Lecture.
Dr. Garret A.
FitzGerald, M.D. Professor of Medicine, Elmer Bobst
Professor of Pharmacology. University of Pennsylvania School of
Medicine
Philadelphia, PA
Title: Cardiovascular consequences of prostaglandin inhibition.
Oct. 3, 2006
Dr. Donna
Wolfe, Ph. D, Assistant
Professor of Medicine, Thomas
Jefferson University, Philadelphia, PA.
Title: Akt-dependent pathways in platelet function.
Oct. 10, 2006
Dr. Fayez F.
Safadi, Ph. D. Associate Professor
Department of Anatomy, Temple University School of Medicine,
Philadelphia, PA.
Title: "Matrix and Transmembrane Proteins-Integrin Interaction in
Osteoblasts"
Oct. 17, 2006
Dr. Bradford
Jameson, Ph.D. Professor of Biochemistry, MCP
Hahnemann University, Philadelphia, PA.
Title: Serotonin mediates the immune response.
Oct. 24, 2006
Dr. Masumi Eto,
Ph. D. Associate Professor of Medicine, Thomas
Jefferson University, Philadelphia, PA.
Title: Mechanisms for Ca2+ sensitizing force of vascular smooth muscle.
Oct. 31, 2006
Dr. Robert W.
Colman, MD. Sol Sherry Professor of Medicine, Temple
University School of Medicine, Philadelphia, PA.
Title: New insights from the structure function analysis of the
catalytic region of human platelet PDE3A.
Nov. 7, 2006
Dr. Alan D.
Michelson, M.B., B.S. Director, Center for Platelet
Function Studies, Professor of Pediatrics, Medicine, and Pathology,
Vice Chair
for
Academic Affairs, Department of Pediatrics, University of Massachusetts
Medical School, MA.
Title: Measurement of Platelet function in patients with coronary
artery disease: How and Why?
November 14, 2006
Dr. Yale
Nemerson, MD. Philip J. and Harriet L. Goodhart Professor of
Medicine and Biochemistry, Mount Sinai School of Medicine, NY.
Title: "Tissue Factor and Lipids: A Coordinated View."
November 28, 2006
Dr. Marilyn
Woolkalis, Ph. D. Associate Professor, Department of
Physiology, Thomas Jefferson University, Philadelphia, PA.
Title: Regulating prothrombotic signaling in human endothelial cells
December 5, 2006
Dr. Barbara
Schick, Ph. D. Professor of Medicine, Thomas Jefferson
University, Philadelphia, PA.
Title: Role of secratory granule proteoglycan in platelet
function.
December 19, 2006
Dr. Zissimos
Mourelatos, M.D., Assistant Professor, Department of
Pathology and Laboratory Medicine, University of Pennsylvania, PA.
Title: It is a small RNA world, after all
January 23, 2007
Dr. Doina
Ganea, Ph. D., Professor, Department of Physiology, Temple
University School of Medicine, Philadelphia, PA.
Title: Neuropeptides and Autoimmune Diseases
January 30, 2007
Dr. Fabio M.
Pulcinelli PhD, MD, Department of Experimental Medicine,
University "La Sapienza" Viale Regina Elena, Roma, Italy
Title: "Impaired platelet COX-1/aspirin interaction in patients under
chronic treatment"
February 6, 2007
Dr. Evgeny
Krynetskiy, Ph.D. Associate Professor Temple University
School of PharmacyPhiladelphia, PA
Title: "Pharmacogenomics: search for individualized therapy".
February 13, 2007
Dr. Lin Wu, MD,
PhD, Research Associate, Albany Medical College,
Cardiovascular Department, Albany, NY
Title: CHARACTERIZATION OF TRANSGENIC MICE WITHA HYPOMORPHIC
NADPH-CYTOCHROME P-450REDUCTASE ALLELE FUNCTIONAL STUDY OF P37 PROTEIN
DURING THE TUMOR METASTASIS
February 20, 2007
Dr. Raul A.
DeLa Cadena, M.D. Associate Professor of Physiology, and
Thrombosis Research, Temple University School of Medicine
Title: “Thrombospondin-1/Neutrophil Interaction: A Pro-Inflammatory
Pathway in Rheumatoid Arthritis”
February 27, 2007
Dr. Michael
Autieri, Ph.D. Assistant Professor of Physiology, Temple
University School of Medicine, Philadelphia, PA.
Title: "the role of inflammatory proteins in vascular proliferative
diseases"
March 6, 2007
Dr. Victor
Rizzo, Ph.D., Associate Professor, Anatomy and Cell Biology,
Temple University School of Medicine, Philadelphia,
PA.
Title: "Participation of endothelial cell membrane rafts and caveolae
in β1 integrin-mediated mechanotransduction".
March 13, 2007
Dr. Louis M
Weiner, M.D. Professor and Vice President, Translational
research and Chairman, Department of Medical Oncology, Temple
University School of Medicine, Philadelphia, PA.
Title: "Unconjugated Antibodies for Cancer Therapy".
March 20, 2007
Dr. Satoru
Eguchi, M.D., Ph.D, Associate Professor of Physiology,
Cardiovascular Research Center, Temple University School of Medicine,
Philadelphia, PA.
Title: Novel signal transduction mechanism of GPCR-induced vascular and
endothelial dysfunction.
April 3, 2007
Dr. Zia
Shariat-Madar, Ph.D The University of Mississippi, Department
of Pharmacology School of Pharmacy
Title: Increased prolylcarboxypeptidase activation is an independent
risk factor for the development of inflammation
April 10, 2007
Dr. Douglas
Cines, M.D., Professor, Department of Pathology, Hospital
of University of Pennsylvania, PA.
Title: Heparin-Induced Thrombocytopenia.
April 17, 2007
Dr. Leon
Salganecoff, Ph.D. Professor Emeritus, Department of
Pharmacology, Temple University School of Medicine, Philadelphia,
PA.
Title: “Dynamics of the adhesion between platelets during
deconsolidation induced by PGE1
April 24, 2007
Dr. Paul Bray,
MD., Professor of
Medicine, Chief of Hematology and Director of Cardeza Foundation
for Hematologic Research, Thomas Jefferson University, Philadelphia, PA.
Title: Measuring Extremes of Platelet Reactivity
May 22, 2007
Dr. Alexandra
Monroy PhD., Assistant Professor, Deaprtment of Anatomy and Cell
Biology, Temple University School of Medicine, Philadelphia,
PA.
Title: Chromatin remodeling factor SRCAP
2006-7 Seminar
coordinator
Dr. Mohammad M. H.
Khan MD., Ph.D.
Sol
Sherry Thrombosis Research Center, 3400 North Broad Street,
Philadelphia, PA 19140
Speakers
2007-2008
September 20, 2007 – Weidong Xiao,
Ph.D.
“AAV Vector: From Basic Science to Gene Therapy”
Children’s Hospital of Philadelphia, Philadelphia
September 28, 2007 – Lawrence Goldfinger
“Developing a new language for cell signaling: Proteomic mapping of Ras
signaling networks in vascular function”
Divisions of Rheumatology and Hematology-Oncology
Department of Medicine, University of California, San Diego
October 2, 2007 - X. Long Zheng, M.D,
Ph.D.
“Cross Talk Between Procoagulant and Von Willebrand Factor”.
Medical Director, Coagulation Laboratory
The Children's Hospital of Philadelphia
Assistant Professor, Department of Pathology and Laboratory Medicine
The University of Pennsylvania Medical Center, Philadelphia
October 9, 2007 - Wadie F. Bahou, M.D.,
Professor of Medicine
“Classification of Platelet Disorders using Gene Profiling”
Hematology and Vice Dean, SUNY/Stony Brook, New York
October 23, 2007 – Duraiswamy Navaneetham Ph.D.
"Inhibition of Factor XIa and Trypsin by Kunitz Inhibitors, PN2KPI and
BPTI: Role of the P1 Site Residue"
Assistant Professor, Sol Sherry Thrombosis Research Center
Temple University, Philadelphia
October 30, 2007 – Mohammad M.
H. Khan, M.D., Ph.D.
"Role of Bacterial Protease in Septic Shock"
Assistant Professor, Sol Sherry Thrombosis Research Center
Temple University, Philadelphia
November 6, 2007 - Wolfgang
Bergmeier, Ph.D.
“Mice lacking the signaling molecule CalDAG-GEFI represent a novel
mouse model for leukocyte adhesion deficiency (LAD)-III”.
Thomas Jefferson University, Dept. of Medicine and Cardeza Foundation,
Philadelphia
November 13, 2007 – David Walter
Essex, M.D.
"The Role of Reactions Involving Thiols and Disulfides in Platelet
Function"
Associate Professor, University of Texas, Department of
Medicine/Hematology, San Antonio, TX
November 16, 2007 - Silvia Muro, Ph.D.
Vesicular trafficking mediated by ICAM-1: A gate for endothelial
transport of drugs, leukocytes and fibrin".
Research Assistant Professor of Pharmacology
Institute for Translational Medicine and Therapeutics
Institute for Environmental Medicine, University of Pennsylvania
Medical School, Philadelphia, PA
November 20, 2007 – Dr. Satya Kunapuli,
Ph.D.
Protein Kinase C deta: At the crossroads of platelet signaling
Professor, Physiology, Professor, Pharmacology
Co-Director, Sol Sherry Thrombosis Research Center
Temple University, Philadelphia
December 4, 2007 – Dr. Sriram
Krishnaswamy, Ph.D.
“Regulation of the Initiation of Coagulation”
Professor, Howard Hughes Medical Institute, Children's Hospital of
Philadelphia, Philadelphia
December 18, 2007 – Dr. Triantafyllos
Chavakis
"JAM-C in vascular inflammation"
National Institutes of Health, Bethesda, MD 20892
January 8, 2008 – James Daniels, Ph.D.
“The Role of Cbl Family Members in Platelet Activation”
Professor, Pharmacology
Associate Professor, Sol Sherry Thrombosis Research Center, Philadelphia
January 15, 2008 – A. Koneti Rao, M.D.
“Signaling Defects in Human Platelets: Phospholipase C-ß2
Expression and NFκB”
Director, Sol Sherry Thrombosis Research Center
Section Chief, Hematology, Professor, Medicine
Professor, Sol Sherry Thrombosis Research Center
Professor, Pathology and Laboratory Medicine, Professor, Pharmacology
Temple University, Philadelphia
January 22, 2008 - – Dr. Charles S.
Abrams, Ph.D.
“How membrane phospholipids affect the platelet cytoskeleton"
Associate Professor of Medicine
University of Pennsylvania, Philadelphia
January 29, 2008 - Linda Knight, Ph.D.
"Radiolabeled Bitistatin: From viper venom to clinical trials as a
diagnostic agent for imaging thrombi in vivo"
Professor of Diagnostic Imaging
Temple University, Philadelphia
February 5, 2008 – Donald L. Gill, Ph.D
“Novel Transduction Mechanisms Controlling Calcium Signals”
Professor and Chair, Department of Biochemistry,
Temple University School of Medicine, Philadelphia
February 12, 2008 - Dr. Donna Woulfe,
Ph.D,
"Akt signaling in platelets: upstream, downstream and inside-out"
Assistant Professor
Center for Translational Medicine
Jefferson Medical College
Thomas Jefferson University, Philadelphia
February 19, 2008 – Syed Ahmad, M.D.,
Ph.D.
“The Assembly of Coagulation Proteins on the Activated Human Platelet
Membranes”
Professor, Sol Sherry Thrombosis Research Center
Professor, Biochemistry
Temple University, Philadelphia
February 26, 2008 - Robert W. Colman,
M.D.
“Plasma Kininogen: A Target for Therapy of Inflammatory and
Neoplastic Disorders”
Professor of Medicine, Professor, Physiology
Professor, Microbiology and Immunology
Professor, Fels Institute for Cancer Research and Molecular Biology
Temple University, Philadelphia
March 4, 2008 - Yi
Wu, M.D., Ph.D.
“Kininogen Targets Endothelial Progenitor Cells in Angiogenesis: New
Life to an Old Story”
Assistant Professor, Sol Sherry Thrombosis Research Center
Temple University, Philadelphia
March 11, 2008 - Mohammad F. Kiani,
Ph.D.
“The Inflammatory Response in Normal and Irradiated Tissue”
Professor and Chair, Department of Mechanical Engineering
Temple University, Philadelphia,
March 25, 2008 – M. Anna Kowalska,
Ph.D.
“Chemokiens and Thrombogenecity”
Department of Hematology
The Children’s Hospital of Philadelphia, Philadelphia
April 1, 2008 - Michael
Bromberg, M.D., Ph.D.
“Role of Tissue Factor-Mediated Signaling in Breast Cancer”
Associate Professor, Medicine
Associate Professor, Sol Sherry Thrombosis Research Center
Temple University, Philadelphia
April 15, 2008 – Rodney M. Camire,
Ph.D.
“Targeting the common pathway for improving hemostasis in hemophilia”
Assistant Professor of Pediatrics
Department of Pediatrics
The Children’s Hospital of Philadelphia, Philadelphia
April 22, 2008 – Andrei
Thomas-Tikhonenko, Ph.D
“MYC v. Thrombospondin & Co: The miRanda ruling upheld”
Associate Professor of Pathology
Department of Pathobiology
University of Pennsylvania, Philadelphia
April 29, 2008 – Michael P. Reilly,
Ph.D.
“Preclinical Mouse Model of Heparin-Induced Thrombocytopenia and
Thrombosis”
Associate Professor of Medicine
Cardeza Foundation for Hematologic Research
Jefferson Medical College
Philadelphia
May 6, 2008 – Mauricio
J. Reginato, Ph.D.
“Breast Cancer in 3D: Mechanisms of Her2/ErbB2-Mediated Oncogenesis”
Assistant Professor
Department of Biochemistry and Molecular Biology
Drexel University College of Medicine
Philadelphia
May 13, 2008 – Kathy
High, M.D.
“Stewart-Niewiarowski Memorial Lecture Award Recipient”
“Gene therapy for genetic disease: the long and winding road”
Professor of Pediatrics
Children’s Hospital of Philadelphia, Philadelphia
May 20, 2008 - Dr.
Xiaoping Du, M.D., Ph.D.
“Signaling pathways of platelet adhesion receptors GPIb-IX and integrin
alpha IIb/beta 3.”
Professor
Department of Pharmacology
University of Illinois at Chicago, Chicago
May 27, 2008 – Dipali
Sinha, Ph.D.
"A tale of one substrate and two enzymes"
Associate Professor, Sol Sherry Thrombosis Research Center
Temple University, Philadelphia
2007-8 Seminar
coordinator
Dr. Gauthami
Jalagadugula Ph.D.
Sol
Sherry Thrombosis Research Center, 3400 North Broad Street,
Philadelphia, PA 19140
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