BEAVER COLLEGE

Department of Chemistry

Chemistry 201-L: Organic Chemistry Laboratory I

Instructor: Dr. Linda Mascavage Boyer Hall, Rm. 303

NOTES:

1. To be eligible for this course you must be concurrently enrolled in, or satisfactorily completed, CH 201.
2. ALL LAB STUDENTS MUST WEAR SAFETY GLASSES OR SAFETY GOGGLES AT ALL TIMES. Students without approved eye protection will NOT be permitted to perform experiments. Any student dismissed from the lab for not following this safety rule will not be permitted to make up the experiment. Warnings will not be repeatedly given.
Prescription eyeglasses, which are not sunglasses, may qualify as safety glasses only if they have side and top shields. Contact lenses may NEVER be worn in lab.
3. Safety in the laboratory is everyone's business. You must follow the directions of the instructor and lab text. Keep alert for unsafe practices and seek to correct them.
4. Students who withdraw from the course must complete "Check-out". Failure to do so may result in a course grade of "F" on the transcript.

TEXT AND MATERIALS:

Kenneth Williamson, "Macroscale and Microscale Organic Experiments", 3rd ed.; D. C. Heath and Company, 1999. Other required supplies include suitable eye protection and a hard-bound notebook.

GRADING:

Laboratory work (experimental and write-ups) will constitute 25% of the course grade for CHEM 201. An evaluation of "techniques" will also be included as part of the final grade. ("Technique" will include such items as being careful to avoid contamination of community reagents, keeping your work areas clean which includes weighing stations and hood space, taking proper care of equipment, finishing on time, working responsibly and independently, improvement of lab skills, etc.)
Lab notebooks will be collected frequently throughout the semester. Due dates will be announced in ample time. Typically, lab reports are due the week following completion of the experimental work. One letter grade will be deducted for EACH day reports are overdue. NO reports will be accepted for grading after class notebooks have been returned. "Prelab" grading will also influence the final grade for each report.

THE FOLLOWING PRACTICES ARE STRICTLY PROHIBITED AT ALL TIMES:

1. Eating, drinking or smoking in the laboratory.
2. Performing, or attempting to perform, unauthorized experiments.
3. Unauthorized removal of chemicals or equipment from the laboratory.
4. Disregard of safety rules.

SCHEDULE:

Brief "prelab" discussions will be given the previous week. The TENTATIVE experimental schedule appears below:

Dates:	Topic
9/7, 9	"Sign-In" and introductory lab lecture
9/14, 16	Expt. 3.2: Crystallization of Phthalic Acid; Expt. 3.5: Crystallization of Benzoic Acid; Expt. 4.2, 4.4: Melting Points of Benzophenone and Unknowns
9/21, 23	Expts. 3.2, 3.5, 4.2, 4.4: continued
9/28, 30	Expt. 8: Partition Coefficient of Benzoic Acid in H2O/CH₂Cl₂ (Mayo text: Micro- and semi-macroscales for Part A)
10/5, 7	¹H NMR Demonstration; Expt. 8: mass, m pt
10/12, 14	Expt. 5.2, 5.3: Simple/Fractional Distillations (macroscale)
10/19. 21	¹H NMR - Distillation fractions
10/26, 28	Trimyristen from Nutmeg (Wilcox and Wilcox text)
11/3, 5	Trimyristen: mass, m pt; Expt. 55: HNO3 Oxidation of Benzoin; Expt. 56: NaBH4 Reduction: Hydrobenzoin from Benzil
11/9, 11	Expts. 55, 56: mass, m pt, 1H NMR; "make up/catch up" lab time
11/16, 18	Expt. 21 - Cyclohexene from Cyclohexanol (macroscale)
11/31, 12/2	Expt. 21: ¹H NMR; begin "Sign-Out" procedures
12/7, 9	"Sign-Out"