COURSE DESCRIPTION:

The class meets for one session of two hours and fifty minutes each week.

• 1). Mayo, D. W., et al. "Microscale Organic Laboratory ..." , 4th edit., J. Wiley & Sons , New York, 2000.
• 2). Eye Protection that meets ANSI standards
• 3). "General Safety Guidelines for CST Labs" including the release waiver**
• 4). A "memory stick" or similar USB device or several 3.5 inch floppy disks
• 5). A hardbound composition book for record keeping and some laboratory notes. Some laptop computers are available in the laboratory.

Supplementary material for the Laboratory is available on line at http://photon.chem.temple.edu which can be accessed from any computer ON CAMPUS or, if off campus, by adjusting the proxy of their browser as directed here ..

SCHEDULING:

The FIRST LABORATORY DAY IS MONDAY, 28 August 2005 .

Your Organic Chemistry 193 lab is scheduled (in BE 409) for only one meeting per week. Students are expected to arrive on time. During the "wet-lab" portion of the course (vide infra), every student will bring with them a carbon copy ("carbon paper" is provided) of the prelab write-up that appears in their respective laboratory notebooks.

You should also be prepared for the quiz that begins every lab.

The schedule below is divided into two portions. The first three classes are different from the last eleven, For the first three, you will be expected to meet in the laboratory room for discussion prior to learning to work with molecular modeling software. Those programs ["Spartan ES" and "WebMO"] will be available for your use throughout the entire semester! The last eleven meetings of the term will be spent in the laboratory to which you are now assigned doing BENCH WORK - more traditional for this course. You should plan now on having your "Safety Guidelines for CST Labs" and eye protection. YOU WILL NOT BE PERMITTED TO WORK IN THE LABORATORY UNLESS YOU ARE WEARING EYE PROTECTION AND ARE DRESSED APPROPRIATELY! . Thus, in addition to safety glasses (contact lenses are not to be worn as organic solvents getting between your iris and the lens can damage your eyes) you are also expected to wear sufficient clothing and foot protection so that dropped objects (flasks, pipettes,etc.) will not injure you and you will not be unprotected in the event of accidental spills.

As is usual for laboratory work, a written report, describing what you did (and using the appropriate software for drawing reactions and inserting spectra into your report) in the previous week's laboratory is to be turned in at the beginning of each lab. It will be graded and returned to you by the following week.

The curriculum for the first three sessions...

Initially, you are expected to learn to use the graphics editor in WebMO, at your convenience, during the first three weeks of class by going to the commercial website to be found by clicking here . The sixth item down on the left-hand column allows you to access the editor. The eleventh item allows you to participate in lessons! However, this commercial version allows you only two minutes of CPU time when attempting a computation. Our version at Temple uses the same editor and allows you more time. You will be assigned a password for our system during the term. You will also have the use of laptop computers in the laboratory for this purpose.

• Laboratory quizzes/computer hand-in.....30%
• Laboratory Notebooks..........................30%
• Last laboratory quiz...............................30%
• Technique* ...........................................10%

Performance on the last quiz above minimum standards is required to pass the course.

*Technique will include items such as being careful to avoid contamination of common reagents, remembering to keep your work area clean, taking care of the equipment including re-hanging automatic delivery pipets, finishing on time, recapping reagent bottles, returning equipment to the location found, keeping only originally inventoried drawer items, etc . The ability of a section to maintain the cleanliness around balances, sorting paper waste, sharps, and broken glass and then placing these items into the proper container, as well as returning stirrer/hot plates and sand baths, will provide a measure for that section's average.

• 1. Long hair be tied back
• 2. Closed footwear be worn (open-toed shoes/sandals are not acceptable)
• 3. Scarves, veils, etc. be tied back or removed during the lab.
• 4. A general understanding that clothing serves as a good barrier between the laboratory environment and skin.

You will be asked to leave the class if your pre-lab preparation is insufficient, if you do not dress appropriately or lack eye-protection, or arrive late (when there is insufficient time to perform the experiment). Missing more than one quiz and failing to write up a lab may effect your grade.

The course is structured to assist you develop skills in several areas considered in lecture and the lab.

• 1. Molecular modeling programs will be introduced and available to enable you to construct and manipulate structures considered in lecture or your lab texts.
• 2. General safety protocols for the laboratory will be enforced.
• 3. A formal, permanent, hardbound laboratory notebook will be maintained - with a detailed pre-lab copy prepared in order for each student to perform successfully in the weekly quiz on the experiment to be performed.
• 4. Techniques and microscale organic lab skills will be developed to permit the flexibility of choosing your own scaling sequence without being tied to a prescribed set of quantities.
• 5. Methods of characterization of organic materials at the microscale will be utilized.
• 6. Successful completion will provide a foundation from which you can develop an expertise in microscale techniques as well as the confidence gained by mastering any challenging program.