Professor Scott Sieburth — Selected Publications

S. McN. Sieburth, H. K. O'Hare, J. Xu, Y. Chen and G. Liu, "Asymmetric Synthesis of a-Amino Allyl, Benzyl and Propargyl Silanes by Metalation and Rearrangement " Organic Letters 2003, 5, 1859-1861.

S. McN. Sieburth, "Photochemical Reactivity of Pyridones" in CRC Handbook of Organic Photochemistry and Photobiology, W. Horspool, Ed., 2nd Ed., CRC, 2003, pp 103-1 – 103-18.

M. wa Mutahi, T. Nittoli, L. Guo and S. McN. Sieburth, "Silicon-Based Metalloprotease Inhibitors: Synthesis and Evaluation of Silanol and Silanediol Peptide Analogs as Inhibitors of Angiotensin-Converting Enzyme (ACE)" Journal of the American Chemical Society, 2002, 124, 7363-7375.

J. Kim, A. Glekas and S. McN. Sieburth, "Silanediol-Based Inhibitor of Thermolysin" Bioorganic and Medicinal Chemistry Letters, 2002, 12, 3625-3627

Y.-H. Lim, K. F. McGee, Jr. and S. McN. Sieburth, "Studies in Bicyclo[3.1.0]hexane Methanolysis. Ring Opening of Activated Cyclopropanes under Acidic and Basic Conditions" Journal of Organic Chemistry 2002, 67, 6535-6538.

M. Zhu, Z. Qiu, G. P. Hiel and S. McN. Sieburth, "Photocycloaddition of Four-Carbon-Tethered Pyridones. Intramolecular Hydrogen Bonding and Facilitated Amide Hydrolysis by a Proximal Secondary Alcohol" Journal of Organic Chemistry2002, 67, 3487-3493.

T. A. Ader, C. A. Champey, L. V. Kuznetsova, T. Li, Y.-H. Lim, D. Rucando and S. McN. Sieburth, "Polyquinanes by [4 + 4] Cycloaddition– Transannular Cyclization" Organic Letters, 2001, 3, 2165-2167.

Y. Chen, T. Li and S. McN. Sieburth, "Pyridone Annulation by 4+2 Coupling of Dienolates with Nitriles and Nitrile Equivalents. A Solution to the Acetonitrile Problem" Journal of Organic Chemistry, 2001, 66, 6826-6828.

C.-A. Chen, S. McN. Sieburth, A. Glekas, G. W. Hewitt, G. L. Trainor, S. Erickson-Viitanen, S. S. Garber, B. Cordova, S. Jeffries, and R. M. Klabe, "Drug Design with a New Transition State Analog of the Hydrated Carbonyl: Silicon-Based Inhibitors of the HIV Protease" Chemistry & Biology, 2001, 8, 1161-1166.

K. F. McGee, Jr., T. H. Al-Tel and S. McN. Sieburth, "Fusicoccin Synthesis by Intramolecular [4 + 4] Photocycloaddition of 2-Pyridones: Stereocontrol of the Cycloaddition and Elaboration of the Pentacyclic Product" Synthesis, 2001, 1185-1196.

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